To investigate possible problems or questions in safety and effectiveness of salmeterol and fluticasone in patients with chronic obstructive pulmonary disease (bronchitis chronic / emphysema). In this special drug use investigation, onset of pneumonia shall be handled as the priority investigation item.

Inclusion Criteria:

• Must use salmeterol and fluticasone for the first time

Exclusion Criteria:

• Patients with hypersensitivity to salmeterol and fluticasone
• Patients with infection which salmeterol and fluticasone is not effective
• Patients with deep mycosis

Patients who are diagnosed as having a chronic obstructive pulmonary disease (bronchitis chronic / emphysema)