Effect of Diet Orange Soda on Urinary Lithogenicity

Effect of Diet Orange Soda on Urinary Lithogenicity

Beverages containing citrate may be useful in increasing urine citrate content and urine pH. Such changes in urine chemistry could help prevent kidney stones. Diet orange soda has more citrate than other similar beverages. The investigators are interested in whether diet soda will improve urine chemistry in the appropriate manner.

The effect of orange soda compared with water in changing 24 hour urine citrate excretion in mg/day will be determined.

Inclusion Criteria:

• 18-65 years old
• able to sign consent
• ability to reliably urinate into a vessel and measure urine volume

Exclusion Criteria:

• prior history of nephrolithiasis
• a known history of metabolic bone disease
• hyperthyroidism
• hyperparathyroidism or chronic kidney disease
• current use of diuretics
• current use of potassium citrate or other oral alkali supplementation and
• use of calcium supplementation that could not be stopped