Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo

Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo in Acute Nonarteritic Anterior Ischemic Optic Neuropathy

In this study 16 Patients diagnosed with Nonarteritic Anterior Ischemic Optic Neuropathy(NSION) who had a sudden mono ocular vision loss associated with optic disc edema and positive Marcus Gunn in less than 30 days without exclusion criteria are randomly divided in two groups 1) control 2) case. In case group Avastin and Triamcinolone will be injected trough vitreal and placebo will be injected in control group. BCVA and Visual field will be then measured in these two groups.

Inclusion criteria:

• Sudden mono ocular vision loss associated with optic disc edema and positive Marcus Gunn (<30 days)

Exclusion criteria:

• Any eye disease except NAION(Nonarteritic Anterior Ischemic Optic Neuropathy)
• Neurologic defect
• Abnormal ESR, CRP, any history of retina or vitreal surgery
• Severe corneal opacity which makes retina examination impossible