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| Name | Class |
|---|---|
| Swedish Cancer Foundation | OTHER |
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The purpose of the study is to compare self-reported health related quality of life after two different operating techniques for low rectal cancer operated by rectal amputation, using a specific and detailed questionnaire. The population has been operated over a 6 year period in one university hospital.
Low rectal cancer treated by abdominoperineal resection (APR, rectal amputation)has worse prognosis than other rectal cancers, both regarding local recurrence and cancer specific survival. With a view to improve local recurrence rates a more extensive perineal operation (excision of the levator muscle) has been suggested. In our university hospital thie technique was introduced for all surgeons January 2007. A population of all patients operated from 1 January 2007 to 31 December 2009 was compared to all patients operated from 1 January 2004 to 31 December 2006 using the traditional, less extensive method, in all a six year period and 158 patients.
A specific questionnaire was developed after in depth interviews, and was face-validated by patients who had undergone an APR. This questionnaire will be sent out to all patients in our population who are still alive.
The patients will be contacted first by a letter of invitation, later called by telephone to be given more information and asked for permission to send the questionnaire.
The send out of invitation letters will start March 2011.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Excision of the levator muscle | The abdominal part of the operation is performed as an TME and the perineal part of the operation is performed with the intent to get a cylindrical specimen thus removing part of or the entire levator muscle with the specimen |
| |
| Traditional perineal operation | The abdominal part of the operation performed as a TME. The perineal operation performed with the intent of removing the tumour with CRM free of tumour and the levator left in place |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Excision of the levator muscle | Procedure | Cylindrical perineal excision including the levator muscle |
|
| Measure | Description | Time Frame |
|---|---|---|
| Health Related Quality of life after rectal cancer surgery - possible differences due to choice of procedure | A detailed questionnaire with 250 questions, where emphasis is on physical satisfaction and emotional status as well as bowel function, sexual function and stoma function 2-7 years after rectal amputation | 2-7 years after operation |
| Measure | Description | Time Frame |
|---|---|---|
| Impact of rectal cancer surgery on household finances in a long-term perspective | Part of the questionnaire deals with the patients'/spouses' career and economic situation after the operation. | 2-7 years after operation |
| Impact of rectal cancer surgery and the level of intrusive thoughts |
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Inclusion Criteria:
Exclusion Criteria:
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colorectal section of one university hospital
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| Name | Affiliation | Role |
|---|---|---|
| Eva Angenete, MD,PhD | Dept. of Surgery, Sahlgernska Univesity Hospital/Ostra | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dept. of Surgery, Sahlgrenska University Hospital/Ostra | Gothenburg | SE 416 85 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25311774 | Derived | Angenete E, Asplund D, Andersson J, Haglind E. Self reported experience of sexual function and quality after abdominoperineal excision in a prospective cohort. Int J Surg. 2014 Nov;12(11):1221-7. doi: 10.1016/j.ijsu.2014.10.003. Epub 2014 Oct 12. |
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| ID | Term |
|---|---|
| D012004 | Rectal Neoplasms |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
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| ID | Term |
|---|---|
| D000078542 | Proctectomy |
| ID | Term |
|---|---|
| D000099090 | Surgical Procedures, Colorectal |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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|
Part of the questionnaire analyses occurrence and effects of intsrusice thoughts |
| 2-7 years after operation |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |