Genetic Polymorphism and Israeli Top-level Swimmers' Perf... | NCT01319032

Studies
Genetic Polymorphism and Israeli Top-level Swimmers' Performance and Expertise

NCT01319032

Sponsor

Hillel Yaffe Medical Center

Status

Unknown status

Last Update Posted

Mar 21, 2011Estimated

Enrollment

200Estimated

Phase

Not provided

Conditions

Genetic Polymorphism Connected to Top-level Swimmers

Interventions

Extraction of whole blood

Countries

Israel

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Mar 2011

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Not yet recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Apr 2011

Primary Completion Date

Dec 2011Estimated

Completion Date

Dec 2012Estimated

First Submitted Date

Mar 17, 2011

First Submission Date that Met QC Criteria

Mar 17, 2011

First Posted Date

Mar 21, 2011Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Mar 17, 2011

Last Update Posted Date

Mar 21, 2011Estimated

Name	Class
Wingate Institute	OTHER

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Not provided

Is FDA Regulated Device

Not provided

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

In a study conducted in our laboratory few years ago, we genotyped 22 genes in 2 athletic groups (endurance and sprinters) and in age and gender matched nonathletic controls. Few of these genes were found to be associated with athletic performance and area of specificity. Since then a few more genes have been found that are related to athletic performance, and we intend to study various genes related to 3 genetic cascade: genes associated with body fluid balance and homeostasis, genes associated with muscle strength, and genes associated with bioenergy. The results of this study compared with athletic level will provide deeper insight into the genetic mechanisms involved in performance.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

Retention

Enrollment

200Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
I. Top-level swimmers			Other: Extraction of whole blood
II. Control		Other swimmers	Other: Extraction of whole blood

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Extraction of whole blood	Other	Extraction of DNA from whole blood	I. Top-level swimmers II. Control

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Identification of genes associated with swimming performance		One year

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Top-level swimmers
Other swimmers

Exclusion Criteria:

All others

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

13 Years

Maximum Age

40 Years

Standard Ages

ChildAdult

Study Population

Swimmers training at the Wingate Institute

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Sigal Ben Zaken, PhD	Contact	972-52-2209853

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Wingate Institute		Netanya			Israel	Sigal Ben Zaken, PhD

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
26284168	Derived	Ben-Zaken S, Eliakim A, Nemet D, Rabinovich M, Kassem E, Meckel Y. ACTN3 Polymorphism: Comparison Between Elite Swimmers and Runners. Sports Med Open. 2015;1(1):13. doi: 10.1186/s40798-015-0023-y. Epub 2015 Jun 14.