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| ID | Type | Description | Link |
|---|---|---|---|
| 1R21NS069275-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National University of San Marcos, Peru | OTHER |
| National Institute of Neurological Disorders and Stroke (NINDS) | NIH |
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The purpose of this study is to determine whether screening and treatment of tapeworm carriers can decrease community transmission of Taenia solium parasitic infection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Targeted screening | Experimental | Screening for intestinal tapeworm carrier followed by treatment with niclosamide as indicated. |
|
| Education | Active Comparator | Community education about Taenia solium prevention. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Niclosamide | Drug | Single oral dose of niclosamide determined by weight (dose: 11 to 34kg receive 1 gram, 35 to 50kg receive 1.5 grams, over 50kg receive 2 grams) |
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| Measure | Description | Time Frame |
|---|---|---|
| Porcine seroprevalence | Every 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| Intestinal tapeworm prevalence | 16 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Seth E ONeal, MD MPH | Oregon Health and Science University | Principal Investigator |
| Armando Gonzalez, DVM PhD | San Marcos University School of Veterinary Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| San Marcos University | Lima | Peru |
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| ID | Term |
|---|---|
| D013622 | Taeniasis |
| D003551 | Cysticercosis |
| D020019 | Neurocysticercosis |
| ID | Term |
|---|---|
| D002590 | Cestode Infections |
| D006373 | Helminthiasis |
| D010272 | Parasitic Diseases |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D009534 | Niclosamide |
| ID | Term |
|---|---|
| D012458 | Salicylanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
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| Community education campaign | Behavioral | Education about prevention of Taenia solium infection provided in a single short (20 minute) interaction with the participant. Education was verbal with visual aids. |
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| D020809 |
| Central Nervous System Helminthiasis |
| D020807 | Central Nervous System Parasitic Infections |
| D002494 | Central Nervous System Infections |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D012457 |
| Salicylamides |
| D000814 | Aniline Compounds |
| D000588 | Amines |