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| Name | Class |
|---|---|
| American College of Gastroenterology | OTHER |
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To assess attitudes toward screening for esophageal adenocarcinoma (EAC) and Barrett's esophagus (BE) in the community.
To develop a population based clinical risk factor prediction model for the diagnosis of BE and identify novel risk factors for BE which would make population based screening more efficient. This will be an important first step in identifying the target population for BE screening, another crucial component of making screening feasible and efficient
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| with gastroesophageal reflux disease(GERD) | Subjects with gastroesophageal reflux disease (GERD) | ||
| Non-GERD | Subjects with no history of gastroesophageal reflux disease (GERD) | ||
| Barrett's esophagus | Subjects with confirmed barrett's esophagus in Olmsted county |
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| Measure | Description | Time Frame |
|---|---|---|
| The primary outcome from the survey will be the proportion of patients willing to undergo an esophageal capsule study compared to those willing to undergo an endoscopic procedure (Esophagogastroduodenoscopy or transnasal endoscopy) | 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| Study established (age, gender, ethnicity, reflux) and potential risk factors (sleep apnea, visceral adiposity, Helicobacter pylori infection, Metabolic Syndrome)to develop a clinical risk factor model for diagnosis of Barrett's esophagus(BE). | Metabolic Syndrome (ATP III criteria, JAMA 2001; 285: 2486-97.) defined as a combination of clinical disorders that includes the presence of three or more of the following indicators:
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Inclusion Criteria:
Exclusion Criteria:
Cases: BE subjects who
Controls: respondents to the "constipation survey" who
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Olmsted county resident
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic | Rochester | Minnesota | 55905 | United States |
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| ID | Term |
|---|---|
| D001471 | Barrett Esophagus |
| D005764 | Gastroesophageal Reflux |
| ID | Term |
|---|---|
| D011230 | Precancerous Conditions |
| D009369 | Neoplasms |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
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Blood
| 18 months |
| D004066 |
| Digestive System Diseases |
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |