National Taiwan University Hospital is the leading center for care of patients with extracorporeal membrane oxygenation (ECMO). The predictable factors associated with outcomes are still lacking in patients with the ECMO support. The aim of this study is to collect the electrical signals stored in the monitor of intensive care units (ICUs), which are analyzed by the bio-informatics software. The pre-, peri-, and post-ECMO heart rate variability, including linear and non-linear analysis is calculated to address the association with outcomes of patients with ECMO. In addition, we collected the demographics, body temperature, respiratory rate, and blood pressure to investigate the causes of heart rate variability.

Inclusion criteria:Adults patients (aged older than 18 years; less than 90 years old) used ECMO for cardiopulmonary support

Exclusion criteria:

1. Patients used illicit drugs
2. Patients received heart transplantation
3. Patients have the history of arrhythmia

Inclusion Criteria:

• Adults patients (aged > 18 years; less than 90 years old) used ECMO for cardiopulmonary support

Exclusion Criteria:

• Patients used illicit drugs
• Patients received heart transplantation
• Patients have the history of arrhythmia

Patients with the support of extracorporeal membrane oxygenation