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The purpose of this study is to determine whether combined anesthesia will provide better pain control for the postoperative period following gynecological laparoscopy surgery.
Following signing an informed consent patients who are scheduled for gynecological laparoscopy surgery for benign disease will randomized to general vs. combined general and spinal anesthesia.
During the postoperative period data regarding pain level as evaluated by visual analogue scale (VAS), number of doses of pain relief drugs, satisfaction and number of day in hospitalization will be collected from patient charts.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| combined anesthesia | Active Comparator | Patients will receive spinal and general anesthesia for benign laparoscopy gynecological surgery |
|
| Control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Spinal anesthesia with Fentanyl+ Morphine | Procedure | Fentanyl 15 microgram Morphine 0.1-0.5 mg |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain level | Pain level will be evaluated every 4 hours from the time of surgery to discharge | For the first 72 hours following surgery |
| Number of doses of analgesic drugs | Number of doses of analgesic medications will be collected from patients charts. | For the first 72 hours following surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lior Lowenstein, MD, MS | Contact | 050-2061434 | LowensteinMD@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Lior Lowenstein | Rambam Health Care Campus | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rambam Health Care Campus | Recruiting | Haifa | 31096 | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 1449966 | Background | Jones T, Tilsley DW, Wilson CB, Lammertsma AA, Brown G, Brady F, Price PM. Positron emission tomography for tumour assessment. NMR Biomed. 1992 Sep-Oct;5(5):265-9. doi: 10.1002/nbm.1940050512. | |
| 10651671 | Background | Motamed C, Bouaziz H, Franco D, Benhamou D. Analgesic effect of low-dose intrathecal morphine and bupivacaine in laparoscopic cholecystectomy. Anaesthesia. 2000 Feb;55(2):118-24. doi: 10.1046/j.1365-2044.2000.055002118.x. |
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| ID | Term |
|---|---|
| D010146 | Pain |
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010468 | Perceptual Disorders |
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| ID | Term |
|---|---|
| D000775 | Anesthesia, Spinal |
| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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| Rambam Health Care Campus | Not yet recruiting | Haifa | 9602 | Israel |
|
| 12437707 | Background | Kong SK, Onsiong SM, Chiu WK, Li MK. Use of intrathecal morphine for postoperative pain relief after elective laparoscopic colorectal surgery. Anaesthesia. 2002 Dec;57(12):1168-73. doi: 10.1046/j.1365-2044.2002.02873.x. |
| 16751162 | Background | Karaman S, Kocabas S, Uyar M, Zincircioglu C, Firat V. Intrathecal morphine: effects on perioperative hemodynamics, postoperative analgesia, and stress response for total abdominal hysterectomy. Adv Ther. 2006 Mar-Apr;23(2):295-306. doi: 10.1007/BF02850135. |
| D019954 | Neurobehavioral Manifestations |
| D009422 | Nervous System Diseases |