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| Name | Class |
|---|---|
| Instituto Piaget | OTHER |
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The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque. Essential oils and delmopinol mouthrinses are effective to reduce dental plaque accumulation and gingivitis. Also an effect on dental bacteria can be found. The study hypothesis states that there are no differences between the mouthrinses on the reduction of gingivitis and dental plaque accumulation as well on the bacterial counts of Streptococcus mutans, Lactobacillus, aerobic and anaerobic bacteria.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Delmopinol mouthrinse | Experimental | Subjects use the delmopinol mouthrinse |
|
| Control | No Intervention | Subjects with no use of mouthrinse | |
| Essential oils mouthrinse | Experimental | Subjects using the essential oils mouthrinse |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Essential oils mouthrinse | Drug | Commercial mouthrinse with manufacturer's use indication |
|
| Measure | Description | Time Frame |
|---|---|---|
| Loe & Silness Gingival Index (1963) | data collected at the begining of the study and two weeks after mouthrinse usage. | change from baseline in gingival index at two weeks |
| Quigley, Hein & Turesky Dental Plaque Index (1970) | data collected at the begining of the study and two weeks after mouthrinse usage. | change from baseline in plaque index at two weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Streptococcus mutans CFU | data collected at the begining of the study and two weeks after mouthrinse usage. | change from baseline in CFU counts at two weeks |
| Lactobacillus CFU | data collected at the begining of the study and two weeks after mouthrinse usage. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mario F Bernardo, PhD | Faculdade de Medicina Dentária da Universidade de Lisboa | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculdade de Medicina Dentária da Universidade de Lisboa | Lisbon | Lisbon District | 1649-003 | Portugal |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8046559 | Background | Abbott DM, Gunsolley JC, Koertge TE, Payne EL. The relative efficacy of 0.1% and 0.2% delmopinol mouthrinses in inhibiting the development of supragingival dental plaque and gingivitis in man. J Periodontol. 1994 May;65(5):437-41. doi: 10.1902/jop.1994.65.5.437. | |
| 17116159 | Background | Addy M, Moran J, Newcombe RG. Meta-analyses of studies of 0.2% delmopinol mouth rinse as an adjunct to gingival health and plaque control measures. J Clin Periodontol. 2007 Jan;34(1):58-65. doi: 10.1111/j.1600-051X.2006.01013.x. Epub 2006 Nov 20. |
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| Delmopinol mouthrinse | Drug | Commercial mouthrinse with manufacturer's use indication |
|
|
| change from baseline in CFU counts at two weeks |
| Aerobic and anaerobic oral bacteria CFU | data collected at the begining of the study and two weeks after mouthrinse usage. | change from baseline in CFU counts at two weeks |
| 12974527 | Background | Baehni PC, Takeuchi Y. Anti-plaque agents in the prevention of biofilm-associated oral diseases. Oral Dis. 2003;9 Suppl 1:23-9. doi: 10.1034/j.1601-0825.9.s1.5.x. |
| 17035671 | Background | Barnett ML. The rationale for the daily use of an antimicrobial mouthrinse. J Am Dent Assoc. 2006 Nov;137 Suppl:16S-21S. doi: 10.14219/jada.archive.2006.0408. |
| 10743861 | Background | Fine DH, Furgang D, Barnett ML, Drew C, Steinberg L, Charles CH, Vincent JW. Effect of an essential oil-containing antiseptic mouthrinse on plaque and salivary Streptococcus mutans levels. J Clin Periodontol. 2000 Mar;27(3):157-61. doi: 10.1034/j.1600-051x.2000.027003157.x. |
| 3902908 | Background | Gordon JM, Lamster IB, Seiger MC. Efficacy of Listerine antiseptic in inhibiting the development of plaque and gingivitis. J Clin Periodontol. 1985 Sep;12(8):697-704. doi: 10.1111/j.1600-051x.1985.tb00941.x. |
| 12787196 | Background | Ouhayoun JP. Penetrating the plaque biofilm: impact of essential oil mouthwash. J Clin Periodontol. 2003;30 Suppl 5:10-2. doi: 10.1034/j.1600-051x.30.s5.4.x. |
| ID | Term |
|---|---|
| D005891 | Gingivitis |
| ID | Term |
|---|---|
| D007239 | Infections |
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| C073738 | delmopinol |
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