Statin/Vitamin D & Migraine Study

Combined Statin and Vitamin D Therapy for Prophylactic Treatment of Episodic Migraine

The investigators are studying if taking simvastatin and vitamin D together will help prevent episodic migraines. Simvastatin is an FDA approved drug that is typically used to treat high cholesterol and reduce the risk of stroke and heart attack. Vitamin D is a vitamin found in certain foods like some types of fish, and in nutritional supplements. This study is 9 months long. Some people who participate will receive simvastatin and vitamin D, and some people will receive a placebo. A placebo is a "sugar pill" that looks like medication but does not have any active ingredients in it.

The investigators hypothesize that taking vitamin D and simvastatin daily may reduce the number of migraines people who have episodic migraine get.

Inclusion Criteria:

• Age 18 years or older
• Have had migraines for at least 3 years
• Have between 4 and 15 migraines a month
• Able to speak and read the English language

Exclusion Criteria:

• Women who are pregnant or nursing, or planning on becoming pregnant in the next 10 months
• Individuals who have a had a heart attack, stroke, peripheral artery disease, atherosclerotic aortic disease, carotid artery disease, or diabetes
• individuals at high risk for cardiovascular disease