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| Name | Class |
|---|---|
| NSA, LLC | INDUSTRY |
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Dehydrated fruit and vegetable concentrates provide an accessible form of phytonutrient supplementation that may offer cardioprotective effects. This study assessed the effects of encapsulated fruit and vegetable juice powder concentrates on endothelial function and cardiac risk markers in subjects in a randomized, double blind, placebo controlled crossover clinical trial with three treatment arms.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | Placebo capsules are provided by the study sponsor and are identical in appearance to active treatments to ensure blinding. |
|
| Blend 2 | Experimental | Blend 2 - combination of Juice Plus+® Orchard (Fruit) and Garden (Vegetable) blends |
|
| Blend 1 | Experimental | Blend 1 - combination of Juice Plus+® Orchard (Fruit), Garden (Vegetable), and Vineyard (Berry) blends |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blend 1 | Dietary Supplement | Blend 1 consists of a combination of Juice Plus+® Orchard (Fruit), Garden (Vegetable), and Vineyard (Berry) blends |
|
| Measure | Description | Time Frame |
|---|---|---|
| Endothelial Function | Endothelial function as flow-mediated dilatation (FMD) | 8-weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Weight | Measured on a calibrated scale | 8-weeks |
| Lipid panel | Total cholesterol, TG, HDL, LDL, ratio | 8-weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| David L Katz, MD, MPH | Yale-Griffin Prevention Research Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Griffin Hospital | Derby | Connecticut | 06418 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21714890 | Derived | Ali A, Yazaki Y, Njike VY, Ma Y, Katz DL. Effect of fruit and vegetable concentrates on endothelial function in metabolic syndrome: a randomized controlled trial. Nutr J. 2011 Jun 29;10:72. doi: 10.1186/1475-2891-10-72. |
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| ID | Term |
|---|---|
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
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| ID | Term |
|---|---|
| D000072506 | Gardens |
| D000072480 | Farms |
| ID | Term |
|---|---|
| D000383 | Agriculture |
| D013676 | Technology, Industry, and Agriculture |
| D000072182 | Non-Medical Public and Private Facilities |
| D000072499 | Manufacturing and Industrial Facilities |
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| Blend 2 | Dietary Supplement | Blend 2 consists of a combination of Juice Plus+® Orchard (Fruit) and Garden (Vegetable) blends |
|
|
| Placebo | Dietary Supplement | Placebo capsules are provided by the study sponsor and are identical in appearance to active treatments to ensure blinding. |
|
| Insulin | Serum insulin | 8-weeks |
| D009750 |
| Nutritional and Metabolic Diseases |