Methylprednisolone Addition in IVF Treatment of Infertile Couples

Methylprednisolone vs. Placebo to Control Late Follicular Progesterone Elevation in GnRH-Antagonist IVF Cycles

Hypothesis to be tested is whether follicular addition of Methylprednisolone can efficiently control late follicular progesterone rise during IVF treatment

The aim is to investigate any potential advantages of adding cortisone supplementation from the follicular phase onwards with regard to premature luteinization, oocyte quality, embryo quality and pregnancy outcome.

Inclusion Criteria:

• less than 36, more than 10 antral follicles, FSH<12

Exclusion Criteria:

• endometriosis stage III&IV,