Resistance Exercise in Healthy Men | NCT01220037 | Trialant

Resistance Exercise in Healthy Men | NCT01220037 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Young regular diet	Experimental	During the time of the study this group will adhere to a standardized regular diet.	Behavioral: Adhere to a specific standardized diet for 4 days
Young low protein diet	Experimental	During the time of the study this group will adhere to a standardized low protein diet.	Behavioral: Adhere to a specific standardized diet for 4 days
Young high protein	Experimental	During the time of the study this group will adhere to a standardized high protein diet.	Behavioral: Adhere to a specific standardized diet for 4 days
Elderly	Experimental	During the time of the study this group will adhere to a standardized high protein diet	Behavioral: Adhere to a specific standardized diet for 4 days

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Adhere to a specific standardized diet for 4 days	Behavioral	24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Muscle fiber myonuclear and stem cell content		baseline
Muscle fiber myonuclear and stem cell content		12 hours after a single bout of resistance type exercise
Muscle fiber myonuclear and stem cell content		24 hours after a single bout of resistance type exercise
Muscle fiber myonuclear and stem cell content		48 hours after a single bout of resistance type exercise
Muscle fiber myonuclear and stem cell content		72 hours after a single bout resistance type exercise

Contacts/Locations Module

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
24306214	Derived	Snijders T, Verdijk LB, McKay BR, Smeets JS, van Kranenburg J, Groen BB, Parise G, Greenhaff P, van Loon LJ. Acute dietary protein intake restriction is associated with changes in myostatin expression after a single bout of resistance exercise in healthy young men. J Nutr. 2014 Feb;144(2):137-45. doi: 10.3945/jn.113.183996. Epub 2013 Dec 4.