Utility of Renal Biomarkers in Cirrhosis

Utility of Renal Biomarkers in Cirrhotic Patients

Evaluation of kidney function is critical in cirrhotic patients as there is a clear relationship between renal failure and prognosis. The investigators hypothesized that in this population new biomarkers of renal function could help in early detection of acute renal failure and in discrimination between renal and pre-renal causes. Finally the investigators hypothesized that such biomarkers could predict short-term outcome in this population.

Inclusion Criteria:

• Age ≥ 18 years
• Known or suspected cirrhosis
• Suspected ascitis
• Informed consent signed

Exclusion Criteria:

• Proven multifocal hepatocellular carcinoma
• Acute gastric hemorrhage (active or < 2 weeks)
• Known end-stage renal disease or on dialysis before admission
• Recipients of kidney or liver transplants
• Transferred from another institution