Effect of Adaptive Servoventilation on Cardiac Function in Chronic Heart Failure and Cheyne-Stokes Respiration

Effect of Adaptive Servoventilation on Cardiac Function, Exercise Tolerance and Quality of Life in Patients With Chronic Heart Failure and Cheyne-Stokes Respiration

Sleep disordered breathing is common in patients with chronic heart failure. Adaptive servoventilation is a novel method of treatment central sleep apnoea, especially associated with Cheyne-Stokes-respiration. The aim of the study is to investigate effect of adaptive servoventilation on cardiac function, exercise tolerance and quality of life in patients with chronic heart failure.

Inclusion Criteria:

• chronic heart failure with ejection fraction ≤45%
• optimal medical treatment for at least 1 month
• clinical diagnosis of Cheyne-Stokes respiration

Exclusion Criteria:

• unstable heart failure
• stroke
• transient ischemic attack in last 6 months
• pacemaker, cardioverter-defibrillator or resynchronization device implanted less than 6 months before study entrance
• severe chronic obstructive pulmonary disease