Chronic Heart Failure - Cheyne Stokes Respiration - CS2 (3C-study)

Open Randomized Study of Patients With Chronic Heart Failure and Cheyne Stokes Respiration Pattern, Treated With ASV. (Adaptive Servo Ventilator).

An investigation where patients with chronic heart failure and cheyne stokes respiration, treated with adapitve servo ventilator, will improve their cardiac function and quality of life.

Chronic heart failure (HF) is one of the most important public health problems in cardiovascular medicine.

Several patients with chronic heart failure also has Cheyne Stokes respiration pattern. Earlier studies have shown that this respiration pattern improves with Adaptive servo ventilator. We wish to investigate wether this leads to improved cardiac function.

Inclusion Criteria:

• Ejection fraction <40%
• NYHA class III-IV
• Optimized therapy with drugs
• Cheyne stokes respiration pattern > 25% while sleeping
• Age < 85 years
• clinical stability the last month before inclusion.

Exclusion Criteria:

• CABG less then 6 months ago
• PCI treatment less then 3 months ago
• Unstable angina pectoris
• Acute coronary syndrome less then 3 months ago
• Stroke less then 6 weeks ago
• Thoracal myopathy
• Advanced COPD