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| ID | Type | Description | Link |
|---|---|---|---|
| R01MH087481 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
| Rutgers University | OTHER |
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This study is a randomized controlled trial comparing Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) to group counseling (GC) for the prevention of depression in adolescents. The project will: (1) identify adolescents with elevated depressive symptoms but who do not meet criteria for a current mood disorder diagnosis; (2) randomize eligible adolescents to either IPT-AST (N = 100) or GC (N = 100); (3) assess depressive symptoms, depressive disorders, global functioning, interpersonal functioning, comorbid conditions and school related indices at baseline, mid-intervention, post-intervention, and at 6-, 12-, 18-, and 24-month follow-up; (4) examine the effects of IPT-AST on depression and various domains of functioning at each time point; and (5) conduct analyses to examine potential mediators and moderators of the association between IPT-AST and depression outcomes. This study will yield data on the efficacy of IPT-AST relative to GC for the prevention of depressive symptoms and depressive disorders. It will also provide information about the mechanisms of action of IPT-AST and determine for whom IPT-AST is most effective.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IPT-AST | Experimental | Interpersonal Psychotherapy-Adolescent Skills Training |
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| Group Counseling | Active Comparator | Group Counseling |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| IPT-AST | Behavioral | A school-based group prevention program that includes 2 individual pre-group sessions, 8 weekly 90 minute group sessions, an individual mid-group session and 4 booster sessions |
| Measure | Description | Time Frame |
|---|---|---|
| Presence of a Major Depressive Episode, Dysthymia or Depressive Disorder Not Otherwise Specified (NOS) on the Schedule for Affective Disorders for School Aged Children - Present and Life Time Version (K-SADS-PL) | Presence of a depression diagnosis as measured by a semi-structured diagnostic evaluation | Post intervention (approximately 3 months post baseline) |
| Presence of a Major Depressive Episode, Dysthymia or Depressive Disorder NOS on the K-SADS-PL | 6-months post-intervention | |
| Presence of a Major Depressive Episode, Dysthymia or Depressive Disorder NOS on the K-SADS-PL | 12-months post-intervention | |
| Presence of a Major Depressive Episode, Dysthymia or Depressive Disorder NOS on the K-SADS-PL | 18-months post-intervention | |
| Presence of a Major Depressive Episode, Dysthymia or Depressive Disorder NOS on the K-SADS-PL | 24-months post-intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Children's Depression Rating Scale-Revised (CDRS-R) | Scores on the CDRS-R | Post intervention (approximately 3 months after baseline) |
| Children's Depression Rating Scale-Revised | 6-months post-intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jami F Young, Ph.D. | Children's Hospital of Philadelphia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rutgers University | Piscataway | New Jersey | 08854 | United States | ||
| Children's Hospital of Philadelphia |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form | Apr 11, 2011 | Apr 5, 2021 | ICF_000.pdf |
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| Group Counseling | Behavioral | Usual group counseling as delivered by school counselors; 1 pre-group session, 1 mid-group session, 8 90-minute group sessions, 4 booster sessions |
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| Children's Depression Rating Scale-Revised | 12-months post-intervention |
| Children's Depression Rating Scale-Revised | 18-months post-intervention |
| Children's Depression Rating Scale-Revised | 24 months post-intervention |
| Children's Global Assessment Scale (CGAS) | Assesses global functioning | Post intervention (approximately 3 months following baseline) |
| Children's Global Assessment Scale | 6-months post-intervention |
| Children's Global Assessment Scale | 12-months post-intervention |
| Children's Global Assessment Scale | 18-months post-intervention |
| Children's Global Assessment Scale | 24-months post-intervention |
| Philadelphia |
| Pennsylvania |
| 19146 |
| United States |