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| ID | Type | Description | Link |
|---|---|---|---|
| 71320 | Registry Identifier | IND |
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A internally controlled, single-blinded, randomized controlled trial to investigate the use of Bimatoprost eyelash gel on eyelash growth and appearance in breast cancer patients who suffer from madarosis (loss of eyelashes) due to the side effects of chemotherapy. IND and IRB approval have been obtained.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bimatoprost treated eyelid | Experimental | one eyelid of the patient was randomized to the treatment arm and given the gel to use |
|
| control arm - no gel | No Intervention | the other fellow eyelid of the patient did not receive any treatment until month 4 and the patient crossed over to treating both eyelids |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bimatoprost eyelash gel | Drug | Bimatoprost 0.03% solution was compounded into a gel - patients used on eyelash margin once daily placing gel with a fingertip or Q-tip for 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| eyelash length | eyelash ruler used to measure eyelash length | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| eyelash pigment | blinded grader used digital photos to grade degree of pigment on scale of 1-5 | 6 mos |
| eyelash thickness | blinded grader used digital photos to grade degree of thickness on scale of 1-5 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duke University Medical Center | Durham | North Carolina | 27710 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15577756 | Result | Tosti A, Pazzaglia M, Voudouris S, Tosti G. Hypertrichosis of the eyelashes caused by bimatoprost. J Am Acad Dermatol. 2004 Nov;51(5 Suppl):S149-50. doi: 10.1016/j.jaad.2004.05.002. |
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| ID | Term |
|---|---|
| D007039 | Hypotrichosis |
| ID | Term |
|---|---|
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D000069580 | Bimatoprost |
| ID | Term |
|---|---|
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D003008 | Cloprostenol |
| D011461 | Prostaglandins F, Synthetic |
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|
| 6 mos |
| eyelash amount | blinded grader used digital photos to grade degree of amount by counting lashes | 6 mos |
| eyelash side effects | any side effects (irritation, allergy, iop change, visual acuity, macular edema, uveitis, iris color change, etc... were assessed | 6 mos |
| D011465 |
| Prostaglandins, Synthetic |
| D011453 | Prostaglandins |
| D015777 | Eicosanoids |
| D005231 | Fatty Acids, Unsaturated |
| D005227 | Fatty Acids |
| D008055 | Lipids |
| D012898 | Autacoids |
| D018836 | Inflammation Mediators |
| D001685 | Biological Factors |