Safety and Efficacy Study of Bimatoprost in Japanese Patients With Chemotherapy-Induced Eyelash Hypotrichosis

A Multicenter, Double-masked, Randomized, Parallel-group Study Assessing the Safety and Efficacy of Once-daily Application of Bimatoprost Solution 0.03% Compared to Vehicle to Treat Chemotherapy-induced Hypotrichosis of the Eyelashes in Japanese Subjects

This study will evaluate the safety and efficacy of bimatoprost solution 0.03% compared with vehicle in Japanese adults with hypotrichosis of the eyelashes following chemotherapy treatment.

Inclusion Criteria:

• Have inadequate eyelashes due to chemotherapy treatment
• Treated for solid tumors such as breast or colorectal cancer in early stages where the cancer has not spread outside the primary organ (eg, stage 1, 2 or 3a for breast cancer)
• Have completed chemotherapy treatment for at least 4 weeks but not more than 24 weeks and all side effects related to chemotherapy are recovered, improved or maintained, with the exception of hair loss

Exclusion Criteria:

• Any disease/infection/abnormality of the eye or area around the eye
• Any ocular surgery within 3 months or anticipated need for ocular surgery during the study
• Any permanent eyeliner or implants of any kind or anticipated use of false eyelashes
• Any semi-permanent eyelash tint, dye, curl or eyelash extension application within 3 months
• Use of any over-the-counter eyelash growth product within 6 months or any use of prescription eyelash growth products
• Use of treatments which may affect hair growth (eg, minoxidil) within 6 months except for prior chemotherapy