Study of Enahnced External Counterpulsation to Treat Coronary Heart Disease

A Prospective,Randomized,Open-labeled,and Blind Endpoint Study of Enhanced External Counterpulsation for Patients With Coronary Heart Disease

To investigate the mid- and long-term effect of Enhanced External Counterpulsation combined with guideline-driven standard treatment on patients documented with and/or at high risk of coronary artery disease.

Inclusion Criteria:

• at least one coronary lesion of more than 50% stenosis shown by angiography
• history of acute myocardial infarction(at least one month before)
• history of prior revascularization (Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting)
• typical angina episodes with evidence of myocardial ischemia
• Signed informed consent

Exclusion Criteria:

• Obvious aortic insufficiency, aortic aneurysm, aortic dissection
• Coronary fistula or severe coronary aneurysm
• Symptomatic Congestive heart failure
• Valvular heart disease, congenital heart diseases, cardiomyopathies
• Cerebral hemorrhage within six months, bleeding disorders or identified bleeding tendency;
• Lower limb infection, phlebitis, varicosity, deep venous thrombosis;
• Progressive malignancies or diseases with poor prognosis;
• uncontrolled hypertension, defined as SBP≥180mmHg or DBP≥110mmHg