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This study compares efficacy (i.e. IOP and hypotensive medications) of phaco alone vs. combined phaco plus excimer laser trabeculotomy vs. combined phaco plus trabectome.
Glaucoma is one of the most common reasons for blindness. Usually an elevated drain resistance is the reason, while aqueous humor production is normal. Medical reduction of intraocular pressure (IOP) is first line therapy in most cases. The gold standard of surgical treatment still is trabeculectomy (TE) but TE has a lot of drawbacks. In particular when glaucoma and cataract coexists, the investigators therefore prefer the combined procedure cataract extraction plus excimer laser trabeculotomy (ELT) or plus Trabectome. Indication is cataract and a moderate elevated IOP without medical therapy or a moderate cataract and elevated IOP with medical therapy.
The ELT is performed by an AIDA XeCl-Excimer Laser System (TUI-Laser AG, Germering, 1,2 mJ per burst, burst duration 16 ns, wave length 308 nm, spot diameter 200 µm). 10 foramina were made over 90 degrees of the anterior chamber angle. Trabectome procedure is performed with the Trabectome unit from Neomedix.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| phaco alone | patients w/ diagnosis of open angle glaucoma underwent phaco alone |
| |
| phaco-ELT | patients w/ diagnosis of open angle glaucoma underwent combined phaco plus ELT |
| |
| phaco-Trabectome | patients w/ diagnosis of open angle glaucoma underwent combined phaco plus Trabectome |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| phaco | Procedure | Standard clear cornea phacoemulsification plsu intraocular lens Implantation (phaco) alone |
|
Inclusion criteria:
Exclusion criteria:
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primary care clinic
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| Name | Affiliation | Role |
|---|---|---|
| 01 Studienregister MasterAdmins | UniversitaetsSpital Zuerich | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zurich | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23799932 | Derived | Toteberg-Harms M, Hanson JV, Funk J. Cataract surgery combined with excimer laser trabeculotomy to lower intraocular pressure: effectiveness dependent on preoperative IOP. BMC Ophthalmol. 2013 Jun 24;13:24. doi: 10.1186/1471-2415-13-24. |
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| ID | Term |
|---|---|
| D005901 | Glaucoma |
| D002386 | Cataract |
| ID | Term |
|---|---|
| D009798 | Ocular Hypertension |
| D005128 | Eye Diseases |
| D007905 | Lens Diseases |
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| phaco-ELT | Procedure | Standard clear cornea phacoemulsification plsu intraocular lens Implantation (phaco) plus excimer laser trabeculotomy (ELT) |
|
| phaco-Trabectome | Procedure | Standard clear cornea phacoemulsification plsu intraocular lens Implantation (phaco) plus Trabectome |
|