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| ID | Type | Description | Link |
|---|---|---|---|
| ADOREP 2009-068 | Other Identifier | ADOREP |
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The main objective is to evaluate an osteopathic compression of pterygopalatine node on sleep obstructive apnea syndrome (OSA).
Osteopathic compression will be compared to a placebo manoeuvre. Efficacy will be assessed by measuring pharyngeal collapsibility
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| active osteopathic compression | Active Comparator | osteopathic compression of Pterygopalatine node |
|
| placebo osteopathic compression | Placebo Comparator | placebo osteopathic compression |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| osteopathic compression of Pterygopalatine node | Procedure | osteopathic compression of Pterygopalatine node |
|
| Measure | Description | Time Frame |
|---|---|---|
| pharyngeal critical pressure | The collapsibility of the upper airway will be evaluated by pharyngeal critical pressure,assessed by measuring the intraluminal pressure associated with the cessation of airflow | 30 minutes after osteopathic compression |
| Measure | Description | Time Frame |
|---|---|---|
| pharyngeal critical pressure | The collapsibility of the upper airway will be evaluated by pharyngeal critical pressure,assessed by measuring the intraluminal pressure associated with the cessation of airflow | 48 hours |
| symptoms |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| valerie attali, MD | Federation des pathologies du sommeil | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pathologies Du Sommeil Pitie Salpetriere | Paris | 75013 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29262824 | Derived | Jacq O, Arnulf I, Similowski T, Attali V. Upper airway stabilization by osteopathic manipulation of the sphenopalatine ganglion versus sham manipulation in OSAS patients: a proof-of-concept, randomized, crossover, double-blind, controlled study. BMC Complement Altern Med. 2017 Dec 20;17(1):546. doi: 10.1186/s12906-017-2053-0. |
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| ID | Term |
|---|---|
| D020181 | Sleep Apnea, Obstructive |
| ID | Term |
|---|---|
| D012891 | Sleep Apnea Syndromes |
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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OSA symptoms
| 48 hours |
| adverse events | clinical evaluation of adverse events | 48 hours |
| D020919 |
| Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |