High Versus Normal Protein Diet in Polycystic Ovary Syndrome (PCOS)

Effect of High-protein or Normal-protein Diet on Weight Loss, Body Composition, Hormone and Metabolic Profile in Women With Polycystic Ovary Syndrome From South Brazil: A Randomized Study

The objective of this study is to assess the effects of a high protein (HP) and a normal protein diet (NP) on patients with polycystic ovary syndrome (PCOS) and body mass index (BMI)-matched controls in a sample of southern Brazilian women.

Patients will be randomized to receive high protein (30% protein, 40% carbohydrate, 30% lipid) or normal protein (15% protein, 55% carbohydrate, 30% lipid) during eight weeks.

The investigators hypothesis is that a different diet composition may have influences in changes of the main characteristics of PCOS, like hyperandrogenism and metabolic syndrome.

Inclusion Criteria:

• women of reproductive age
• BMI ranging from 18.5 to 39.9 kg/m²

Exclusion Criteria:

• Use of any drugs known to interfere with hormone levels for at least 3 months before the study
• Women with known type 2 diabetes, liver or renal disease or thyroid dysfunction
• Other hyperandrogenic disorders than PCOS