Atopy patch test in normal population

The initial diagnostic work up of suspected food allergy includes patient's history, skin prick test (SPT), measurement of food specific immunoglobulin E (IgE) with serological assays, and more recently the atopy patch test. A positive SPT seems to reflect early reactions to food challenges, whereas the atopy patch test has a high diagnostic efficacy for late phase clinical reactions. The purpose of this study was to evaluate atopy patch test reaction in non-atopic population.

Inclusion Criteria:

• Healthy volunteer
• Age 18-40 yrs
• Volunteer sign for informed consent

Exclusion Criteria:

• who have dermographism
• who have chronic disease eg.autoimmune disease, immune deficiency, cancer or allergic disease
• pregnant women
• who have severe eczema
• who receive antihistamine, topical steroid and systemic steroid > 20 mg/day within 7 days prior study