Experimental Study to Validate the Modified Glucose Disposal Test

Experimental Medicine Study to Validate the Modified Glucose Disposal Test in Healthy Subjects and Subjects With Type 2 Diabetes

Evaluate the modified GDT as a measure of key metabolic characteristics in healthy subjects and those with type 2 diabetes mellitus

Inclusion Criteria:

• Clinical diagnosis of Type 2 diabetes
• Clinically healthy
• Drug naive or on a stable dose of metformin monotherapy and/or a secretagogue

Exclusion Criteria:

• Type 1 Diabetes
• History of significant heart disease.
• Bariatric surgery
• Exposure to fibrates, thiazolidinediones, insulin, exenatide, pramlintide or DPP-IV inhibitors