Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension. The investigators thesis is that DM and pre-diabetes is prevalent in patients undergoing cardiovascular surgery and to some extend is under-diagnosed. At the same time the investigators imagine that DM is closely related to the degree of arterial stiffness, and that these parameters are closely related to a new biochemical marker, fibulin-1.
The investigators aim to describe the prevalence of type 2 DM and dysmetabolism in patients admitted to the hospital to undergo cardiovascular surgery and besides that to investigate if there is a connection between the degree of the dysmetabolism and arterial disease, by studying arterial stiffness and by measuring a new biochemical marker, fibulin-1, which the investigators newly have identified. The results of this project will give us a measure for the quantity of unknown DM in patients undergoing cardiovascular surgery and furthermore tell us more in terms of the connections between a newly identified plasma arterial marker, arterial stiffness and diabetes.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
The cohort will be selected from patients undergoing planned heart and vascular surgery at our department.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Maria Lyck Hansen, Ph.d student | Contact | 004540828020 | maria.lyck.hansen@ouh.regionsyddanmark.dk | |
| Lars Melholt Rasmussen, Professor, MD | Contact | 0045-6541 4506 | lars.melholt.rasmussen@ouh.regionsyddanmark.dk |
| Name | Affiliation | Role |
|---|---|---|
| Lars Melholt Rasmussen, Professor, MD | Department of Biochemnistry and Farmacology, Odense University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Biochemnistry and Farmacology, Odense University Hospital | Odense | 5000 | Denmark |
Not provided
| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| D001161 | Arteriosclerosis |
| D016893 | Carotid Stenosis |
| D013927 | Thrombosis |
| D017544 | Aortic Aneurysm, Abdominal |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
In this study we will collect serum, whole blood and urine
| D001157 |
| Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002340 | Carotid Artery Diseases |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D016769 | Embolism and Thrombosis |
| D001014 | Aortic Aneurysm |
| D000783 | Aneurysm |
| D001018 | Aortic Diseases |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |