Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Our objective is to determine whether food form (liquid vs. solid) alters gastric emptying, satiety, and food intake, when all macronutrients and fiber are controlled. The study population will include 10 healthy women, who have a normal body mass index. We have chosen to evaluate only women because this is a small pilot study and one of our endpoints is gastric emptying. Gastric emptying is known to differ between men and women. Gastric emptying will be evaluated using the Smartpill technology, satiety will be evaluated using computerized visual analog scales/questions, and food intake will be measured by providing subjects with an ad libitum/buffet-style lunch.
Our hypothesis is that our subjects will be less hungry after they eat a solid breakfast compared to a liquid breakfast. We also hypothesize that our subjects will have a slower gastric emptying time after they eat the solid meal. Lastly, we think subjects will want to eat less food at lunch time if they have eaten a solid meal compared to a liquid meal for breakfast.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Liquid Meal |
| ||
| Solid Meal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Liquid Breakfast | Other | The liquid breakfast meal will contain 370 calories and will consist of fruit juices and skim milk |
|
| Measure | Description | Time Frame |
|---|---|---|
| Determine whether food form (liquid vs. solid) alters gastric emptying time when all macronutrients and fiber are controlled. | Subjects will consume both liquid and solid meals and we will evaluate and compare gastric emptying time after each of them. | May 2010 to December 2010 |
| Measure | Description | Time Frame |
|---|---|---|
| Determine whether food form (liquid vs. solid) alters satiety and food intake when all macronutrients and fiber are controlled. | Subjects will consume both liquid and solid meals and we will evaluate and compare appetite and food intake after each of them. | May 2010 to December 2010 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Healthy women; age 18 - 35; body mass index in the healthy range between 18.5 and 25; proficient English speakers; non-smoking; not taking medications; non-dieting (weight stable over last 3 months); able to swallow a large capsule
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Holly J Willis, PhD | University of Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Saint Paul | Minnesota | 55108 | United States |
Not provided
Not provided
Not provided
Not provided
| Solid Breakfast Meal | Other | The solid breakfast will contain 370 calories and will consist of oatmeal, golden delicious apples, blueberries, skim milk, and brown sugar. |
|