Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia

Study of Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia

It is unclear whether a topical pharyngeal anesthesia adds any benefit to the upper gastrointestinal endoscopy under a propofol sedation. We hypothesize that a topical pharyngeal anesthesia does not ease the upper gastrointestinal endoscopy under propofol sedation. The aim of this study is therefore to quantify the impact of a topical pharyngeal anesthesia to the upper gastrointestinal endoscopy in patients sedated with propofol.

Patients will be randomized to receive a topical pharyngeal spray containing either an anesthetic drug (lidocaine 10%) or a placebo. Thereafter the upper endoscopy will be conducted in its standard manner.

Inclusion Criteria:

• Scheduled diagnostic upper endoscopy
• Wish to be sedated
• ASA class I - III
• Signed informed consent

Exclusion Criteria:

• Emergency medical examinations
• Therapeutic Endoscopy
• ASA class IV
• Pregnancy
• Known allergy to propofol or lidocaine