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| ID | Type | Description | Link |
|---|---|---|---|
| AOL 2008 |
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Primary purpose : to assess the effect on neuropsychological tasks related to planning of 10 daily sessions of right dorsolateral prefrontal cortex with High-frequency repetitive transcranial magnetic stimulation (rTMS) on borderline personality disorder (BPD) patients.
Hypothesis : BPD patients receiving 10 sessions of rTMS will have greater improvement in the average number of move to achieve tasks of the Tower of London, than those receiving sham rTMS.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| rTMS | Experimental | rTMS sessions |
|
| control | Sham Comparator | sham rTMS (control) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| repetitive Transcranial Stimulation Magnetic (rTMS) | Procedure | The motor threshold was determined in each subject once, before treatment. This was defined as the lowest stimulation intensity capable of inducing a visible movement at least five times out of 10 stimulations. The position of the right dorsolateral prefrontal cortex was defined as 5 cm anterior (in a parasagittal line) to the motor cortex. The stimulus intensity was 80% of the patient's motor threshold intensity. Treatments were given for 20 minutes per day over 10 working days. |
| Measure | Description | Time Frame |
|---|---|---|
| Tower of London | Inclusion, 15th day, 30th day and 3rd month |
| Measure | Description | Time Frame |
|---|---|---|
| Balloon Analog Risk Task | Inclusion, 15th day, 30th day and 3rd month | |
| Micro-World Test | Inclusion, 15th day and 3rd month | |
| Borderline Personality Disorder Severity Index |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lionel Cailhol, MD | University Hospital Toulouse - 31059 Toulouse - France | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lionel Cailhol | Toulouse | University Hospital Toulouse | 31059 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24503285 | Result | Cailhol L, Roussignol B, Klein R, Bousquet B, Simonetta-Moreau M, Schmitt L, Thalamas C, Tap G, Birmes P. Borderline personality disorder and rTMS: a pilot trial. Psychiatry Res. 2014 Apr 30;216(1):155-7. doi: 10.1016/j.psychres.2014.01.030. Epub 2014 Jan 30. |
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| ID | Term |
|---|---|
| D001883 | Borderline Personality Disorder |
| ID | Term |
|---|---|
| D010554 | Personality Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D050781 | Transcranial Magnetic Stimulation |
| ID | Term |
|---|---|
| D055909 | Magnetic Field Therapy |
| D013812 | Therapeutics |
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|
| sham rTMS | Procedure | sham rTMS |
|
| Pre-inclusion, 30th day and 3rd month |
| Symptom Check List - 90 | Inclusion, 15th day, 30th day and 3rd month |
| Barratt Impulsivity Scale | Inclusion and 3rd month |
| Global Assessment Scale | Inclusion and 3rd month |