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| Name | Class |
|---|---|
| The Danish Medical Research Council | OTHER |
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The purpose of the study is to determine the importance of the UV intensity and the UVB dose on the Vitamin D response after UVB.
The work is addressing vitamin D production after UVB exposure and explore the importance of UVB dose and UV intensity. Four different UVB doses and four different UV intensities are used to explore these relationships.
Many assumptions have been made concerning the vitamin D production after UVB exposure but only few studies exist.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Active Comparator | UV intensity 10 MIN |
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| Group 2 | Active Comparator | UV intensity 5 MIN |
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| Group 3 | Active Comparator | UV intensity 1 MIN |
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| Group 4 | Active Comparator | UV intensity 20 MIN |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| UVB | Radiation | 0.375 SED x 4 in a week |
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| Measure | Description | Time Frame |
|---|---|---|
| Vitamin D (nmol/l) | Vitamin D measured in a blood sample to define the dose-response relationship between UVB dose, UV intensity and Vitamin D production in the skin after UVB exposure. | 2 days after exposure |
| Measure | Description | Time Frame |
|---|---|---|
| Other parameters | To invesitage whether other parameters like sex, BMI, Diet etc. influences the vitamin D production after UVB exposure. | 2 days after radiation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hans Christian Wulf, Professor | Bispebjerg Hospital, Deparment of Dermatology | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bispebjerg Hospital, Department of Dermatology | Copenhagen NV | NV | 2400 | Denmark |
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| ID | Term |
|---|---|
| D012878 | Skin Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| UVB | Radiation | 0.75 SED x 4 in a week |
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| UVB | Radiation | 1.5 SED x 4 in a week |
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| UVB | Radiation | 3.0 SED x 4 in a week |
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