Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

To evaluate the additive value of tadalafil given together with Diamox (acetazolamide) in preventing acute mountain sickness in travelers to high altitude areas.

A randomized controlled study comparing:

Tadalafil [20mg x1/day] and acetazolamide [125mg x2 day], versus Acetazolamide [125mg x2 day] alone, in trekkers to altitude > 3,000 m.

Inclusion Criteria:

• Participant in trekking to high altitude
• Agreement to sign the informed consent.

Exclusion Criteria:

• No agreement to sign informed consent.