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| ID | Type | Description | Link |
|---|---|---|---|
| P01AT004952 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Center for Complementary and Integrative Health (NCCIH) | NIH |
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This study is focused on the brain mechanisms and peripheral biological correlates of two different forms of meditation--mindfulness-based and compassion/loving-kindness. Project 1 is focused on the impact of compassion/loving-kindness meditation on emotional reactivity and emotion regulation. Project 2 is focused on the neural and behavioral correlates of mindfulness meditation and attention and pain regulation. In addition, Project 2 will examine the relations between changes in oscillatory rhythms during meditation and attention and pain processing. Project 3 will examine the impact of meditation on spontaneous brain activity during sleep. This project will also examine the impact of intensive meditation on regional changes in slow wave activity during subsequent sleep. Each of these projects will be conducted on the same participants so that interrelations among the various measures collected in the different projects can be examined. We believe that this study will dramatically advance the understanding of the mechanisms by which meditation produces changes in behavioral and biological processes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mindfulness Based Stress Reduction | Active Comparator |
| |
| Health Enhancement Program | Active Comparator |
| |
| Wait List Controls | No Intervention | ||
| Long Term Meditators | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Day of intensive meditation practice | Behavioral | Long-term meditators practice for ~6 hours of meditation at each time point |
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| Measure | Description | Time Frame |
|---|---|---|
| MRI BOLD | Pre, Post, Follow-up (WL & LTP) | |
| EEG | Pre, post, & follow-up (WL & LTP) | |
| Salivary Cortisol | Pre, post, & follow-up (WL & LTP) | |
| Behavioral | Pre, post, & follow-up (WL & LTP) | |
| Self-report | Pre, post, & follow-up (WL & LTP) |
| Measure | Description | Time Frame |
|---|---|---|
| Self-report | Pre, post, & follow-up (WL & LTP) |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Richard J Davidson, PhD | UW-Madison | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Wisconsin Sleep Laboratory | Madison | Wisconsin | 53705 | United States | ||
| UW-Health Sports Medicine & Integrative Medicine Program |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35899379 | Derived | Wielgosz J, Kral TRA, Perlman DM, Mumford JA, Wager TD, Lutz A, Davidson RJ. Neural Signatures of Pain Modulation in Short-Term and Long-Term Mindfulness Training: A Randomized Active-Control Trial. Am J Psychiatry. 2022 Oct;179(10):758-767. doi: 10.1176/appi.ajp.21020145. Epub 2022 Jul 28. |
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| Mindfulness Based Stress Reduction (MBSR) | Behavioral | 8-week class designed to enhance well-being through training in mindfulness meditation |
|
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| Health Enhancement Program (HEP) | Behavioral | 8-week class designed to enhance well-being through training in physical activity, functional movement, music therapy, and nutrition |
|
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| Madison |
| Wisconsin |
| 53705 |
| United States |
| UW-Madison, Laboratory for Affective Neuroscience | Madison | Wisconsin | 53705 | United States |
| ID | Term |
|---|---|
| D000092862 | Psychological Well-Being |
| ID | Term |
|---|---|
| D010549 | Personal Satisfaction |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D000099024 | Mindfulness-Based Stress Reduction |
| ID | Term |
|---|---|
| D064866 | Mindfulness |
| D015928 | Cognitive Behavioral Therapy |
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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