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The major aim of treatment for rheumatoid arthritis is remission. Nevertheless, structural radiographic progression is observed in 15 to 20% of patient getting remission. Numerous definitions of the remission proposed by literature remain imperfect.
Recently ultrasonography and MRI seem to be helpful in diagnosis and follow-up of rheumatoid arthritis.
Studies in patients with clinical remission are reporting 75 to 90% of persistent MRI and ultrasonography synovitis, 45% of cases with synovial activity.
To our knowledge, in such case few studies showed correlation between persistent imaging synovitis and structural radiographic progression.
On the other hand, no studies with extremity dedicated RMI in patients with remission are reported.
In this preliminary study, the investigators propose to evaluate in patients with rheumatoid arthritis remission and persistent dedicated MRI synovitis the structural radiographic progression at one year.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dedicated extremity MRI | Other | Structural deterioration radiographic assessed by dedicated extremity MRI |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI | Other | dedicated extremity MRI |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dedicated extremity MRI (hand and wrist)/ X-Ray (hand, wrist and foot) | at Month 0 (first visit) and Month 12 (last visit) |
| Measure | Description | Time Frame |
|---|---|---|
| Ultrasonography (hand, wrist and foot) | at Month 0 (first vist) and Month 12 (last visit) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Christine ALBERT-SABONNADIERE, PhD | Contact | albert-sabonnadiere.c@chu-nice.fr |
| Name | Affiliation | Role |
|---|---|---|
| Christine ALBERT-SABONNADIERE, PhD | Nice University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de NICE | Recruiting | Nice | 06000 | France |
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| Rheumatology Department, Nice University Hospital | Not yet recruiting | Nice | 06000 | France |
|
| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| D013585 | Synovitis |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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