Vitamin D Status and Dose Response in Infants

Vitamin D Status and Dose Response in Infants

This study will examine the relationship of serum 25(OH)D levels in infants 32 weeks and greater gestation who are fed infant formula to markers of inflammation and bone metabolism.

It is hypothesized that serum 25(OH)D levels in infants 32 weeks and greater gestation are not maintained at optimal levels of greater than 32 ng/Ml with currently available infant formulas, and that this will have an inverse relationship with markers of inflammation and bone metabolism.

Inclusion Criteria:

• greater than 32 weeks gestation,
• exclusively formula fed.

Exclusion Criteria:

• less than 32 weeks gestation,
• less than 1500 grams,
• recieving maternal breast milk,
• recieving parenteral nutrition,
• congenital anomolies,
• disorders of vitamin D metabolism,
• inborn errors of metabolism,
• seizure disorders,
• parathroid disease,
• liver, GI tract, or kidney disease, and
• disorders of calcium metabolism.