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The aim of this study is to analyze oral squamous cell carcinoma and healthy oral mucosa for the possible presence of Epstein-Barr virus (EBV).
Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| oral cancer | patients with oral squamous cell carcinoma | ||
| control group | healthy patients without any oral pathology |
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| Measure | Description | Time Frame |
|---|---|---|
| presence of EBV | Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction. | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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oral care clinic, community sample
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| Name | Affiliation | Role |
|---|---|---|
| Glauco Issamu I Miyahara, Professor | Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP | Principal Investigator |
| Lívia T Arêde, student | Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP | Araçatuba | São Paulo | 16025-050 | Brazil |
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| Label | URL |
|---|---|
| School of Dentistry, Sao Paulo State University, Unesp, Araçatuba/SP | View source |
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| ID | Term |
|---|---|
| D009062 | Mouth Neoplasms |
| ID | Term |
|---|---|
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D009059 | Mouth Diseases |
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paraffin-embedded tissue samples
| D009057 |
| Stomatognathic Diseases |