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| Name | Class |
|---|---|
| University of Konstanz | OTHER |
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Definition of the efficacy of NET compared with "treatment as usual" in the treatment of patients with complex traumatic disease (borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD)) as assessed by structured clinical interviews. Furthermore, to evaluate the sleep, cortisol level and epigenetic differences in the process of the specific therapy compared to treatment as usual.
Experimental intervention:
Narrative Exposure Therapy (NET), an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity.
Control intervention:
Treatment as usual.
Follow-up per patient:
3 follow-up assessments- 4 weeks, 6 months,12 months and 24 months after end of experimental/ control intervention
Duration of intervention per patient:
Both treatment types will be conducted for 10-14 sessions of 60-90 min in length.
Additionally 5 sleep laboratory investigations (1 pre- and 4 post- intervention (4 weeks, 6 months, 12 months, 24 months after treatment)) will be carried out. Additionally the cortisol level in the hair and epigenetic markers will be recorded. The estimated observation time is 2 years.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| treatment as usual | Active Comparator | Treatment as usual |
|
| narrative exposure therapy | Experimental | Narrative Exposure Therapy (NET), an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversities |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| narrative exposure therapy | Behavioral | Narrative Exposure Therapy (NET), an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversities |
| Measure | Description | Time Frame |
|---|---|---|
| Clinician-Administered PTSD Scale (CAPS) | 0 - 1 - 6 - 12 - 24 month |
| Measure | Description | Time Frame |
|---|---|---|
| Borderline symptom checklist 23 (BSL) | 0 - 1 - 6 - 12 - 24 |
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Inclusion Criteria:
Exclusion Criteria:
Known severe internal, neurological, musculoskeletal, endocrinological or sleep disorders with organic origin (clinical examination during the screening visit, judged by the investigator)
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zentrum Integrative Psychiatrie | Recruiting | Kiel | 24105 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26970970 | Derived | Weinhold SL, Goder R, Pabst A, Scharff AL, Schauer M, Baier PC, Aldenhoff J, Elbert T, Seeck-Hirschner M. Sleep recordings in individuals with borderline personality disorder before and after trauma therapy. J Neural Transm (Vienna). 2017 Feb;124(Suppl 1):99-107. doi: 10.1007/s00702-016-1536-3. Epub 2016 Mar 12. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jan 27, 2014 | |
| Unrelease | Yes | |
| Release | Jan 28, 2014 |
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| Reset | Mar 11, 2014 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jan 27, 2014 | Yes | |||
| Jan 28, 2014 | Mar 11, 2014 |
| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| D001883 | Borderline Personality Disorder |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
| D010554 | Personality Disorders |
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