Assessment Of The Inhalation Profiles Of Four Dry Powder Inhalers In Patients With Variable Degrees Of Lung Obstruction

A Randomized Cross-Over Study Investigating The Inhalation Profiles Of Four Dry Powder Inhalation Devices In Subjects With Asthma And Chronic Obstructive Pulmonary Disease.

Assessment of the inhalation profiles of four dry powder inhalers in patients with variable degrees of lung obstruction

Randomized to device sequence

Inclusion Criteria:

• Subjects with a physician documented history or diagnosis of asthma for at least 6 months
• Reversibility, defined as an increase in FEV1 at the Screening visit of greater than or equal to 12% and 200 mL
• Subjects with a physician documented history or diagnosis of mild or severe Chronic Obstructive Pulmonary Disease

Exclusion Criteria:

• Female subjects who are pregnant
• Subjects who have a history of life-threatening asthma/COPD or who have experienced two or more exacerbations requiring hospitalization in the 12 months prior to screening
• Evidence of lower respiratory tract infection
• Subjects diagnosed with pulmonary fibrosis, bronchiectasis, pneumoconiosis, sarcoidosis or tuberculosis