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| ID | Type | Description | Link |
|---|---|---|---|
| 20070530 | Other Identifier | Western Institutional Review Board |
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The purpose of this study is to assess the effect of Metabolism-boosting Beverages (MBB) containing green tea extract with a standardized amount of epigallocatechin gallate (EGCG) and caffeine.
The study will assess the effect of MBB's on 24 hour energy expenditure by performing indirect calorimetry, and on appetite using visual analogue scales (VAS). The planned sample size is 54 healthy male and female adults, both lean and overweight. We plan to test 6 metabolism-boosting beverages in the following order: 1) Raspberry Tea 2) Banana Shake 3) Chai Latte 4) Strawberry Shake 5) Cappuccino 6) Hot Cocoa. In the order that they are screened, each subject will be assigned to receive 1 of 6 Metabolism-boosting beverages. Each MBB will contain 90 mg EGCG and 100 mg caffeine.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medifast Metabolism-boosting Beverages | Other | Medifast metabolism-boosting beverages containing 90 mg EGCG and 100 mg caffeine. |
| Measure | Description | Time Frame |
|---|---|---|
| To assess the effect of MBBs on REE by performing indirect calorimetry | 30, 60, 90, and 120 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| To assess the effect of MBBs on appetite via visual analogue scales | 30, 60, 90, and 120 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lisa M Davis, PhD, PA-C | Medifast, Inc. | Principal Investigator |
| Christopher D Coleman, MS,RD,LDN | Medifast, Inc. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medifast Inc. | Owings Mills | Maryland | 21117 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16176615 | Background | Berube-Parent S, Pelletier C, Dore J, Tremblay A. Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men. Br J Nutr. 2005 Sep;94(3):432-6. doi: 10.1079/bjn20051502. | |
| 3165600 | Background | Acheson KJ, Schutz Y, Bessard T, Anantharaman K, Flatt JP, Jequier E. Glycogen storage capacity and de novo lipogenesis during massive carbohydrate overfeeding in man. Am J Clin Nutr. 1988 Aug;48(2):240-7. doi: 10.1093/ajcn/48.2.240. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D015431 | Weight Loss |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001836 | Body Weight Changes |