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| Name | Class |
|---|---|
| Otsuka Pharmaceutical Co., Ltd. | INDUSTRY |
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The purpose of this study is to evaluate the safety and efficacy of rebamipide 2% suspension for the treatment of patients with dry-eye.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| rebamipide 2% ophthalmic suspension | Experimental |
| |
| Placebo eye drops | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| rebamipide 2% ophthalmic suspension | Drug | Instill one drop in each eye four times daily for 12 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Total fluorescein corneal staining score | 4 weeks | |
| Primary ocular discomfort | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Dry eye symptoms | 12 weeks | |
| Ocular staining | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nancy Boman, MD, PhD | Kubota Vision Inc. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Eye Care Group, P.C. | Waterbury | Connecticut | 06708 | United States | ||
| Richard Eiferman, MD |
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| placebo eye drops | Drug | Instill one drop in each eye four times daily for 12 weeks. |
|
| Louisville |
| Kentucky |
| 40205 |
| United States |
| Central Maine Eye Care | Lewiston | Maine | 04240 | United States |
| Ora, Inc | Andover | Massachusetts | 01810 | United States |
| Total Eye Care, P.A. | Memphis | Tennessee | 38119 | United States |
| ID | Term |
|---|---|
| D015352 | Dry Eye Syndromes |
| D007638 | Keratoconjunctivitis Sicca |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
| D007637 | Keratoconjunctivitis |
| D003231 | Conjunctivitis |
| D003229 | Conjunctival Diseases |
| D007634 | Keratitis |
| D003316 | Corneal Diseases |
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| ID | Term |
|---|---|
| C052785 | rebamipide |
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