Coenzyme Q10 in Older Athletes Treated With Statin Medications

A Randomized, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Efficacy of Coenzyme Q10 in Improving Mitochondrial Function in Older Athletes Treated With Statin Medications

The purpose of this study is to evaluate the effect of coenzyme Q10 administration in improving mitochondrial function as measured by anaerobic threshold in older athletes on a stable dose of statin medication.

Inclusion Criteria:

• Patients ≥ 50 years of age, male or female.

• Patients on a stable dose of statin medication for at least 3 months prior to enrollment in the study

• Self-Described Athletes with any of the following characteristics:

  • Participation in a competitive athletic event within the past year or currently training for a competitive athletic event within the 6 months following enrollment
  • Regular exercise activity of at least 45 minutes duration 5 times per week

Exclusion Criteria:

• Use of coenzyme Q10 during the preceding two months.
• CPK level at baseline greater than two times the upper limits of normal
• LDL level at baseline greater than 160 for those without a cardiovascular risk or cardiovascular risk equivalent
• LDL level at baseline greater than 130 for those with a cardiovascular risk or cardiovascular risk equivalent