Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma

Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma

The purpose of this study is to evaluate the efficacy of photodynamic therapy in treatment of Basal cell carcinoma (BCC) and factors that affect response rate.

Background and Aim: Basal cell carcinoma (BCC) is the most common skin cancer .Photodynamic therapy _as a novel , non-invasive therapeutic approach _may be considered a valuable strategy. This study was designed with the aim of the evaluation of efficacy of PDT in treatment of BCC and factors that may affect response rate.

Materials and Methods: This was a clinical trial which was done on 28 BCCs. Patients were treated with ALA-PDT monthly for 1-6 sessions and evaluated for clinical response,cosmetic results and probable side effects.

Inclusion Criteria:

• Histologically proven BCCs

Exclusion Criteria:

• Rodent ulcer
• Morphea type
• ANA +
• History of photosensitivity or photodermatosis or ingestion of phototoxic
• Drugs during last month
• Pregnancy
• Breast feeding
• Age< 18
• History of another therapeutic intervention for bcc during last 6 months