Fractional CO2 Laser Assisted Photodynamic Therapy | NCT01260987 | Trialant

Fractional CO2 Laser Assisted Photodynamic Therapy | NCT01260987 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
AK split-face treatment	Active Comparator	Split-face treatment of two symmetrical areas with moderate to severe actinic keratoses. One area is treated with conventional PDT the other with fractional laser assisted PDT.	Drug: Conventional photodynamic therapy Drug: Fractional CO2 laser assisted PDT
Fractional laser assisted PDT for BCC	Active Comparator	Difficult to treat nodular basal cell carcinomas in the face is pretreated with fractional CO2 laser followed by methyl-aminolevulinate PDT.	Drug: Fractional CO2 laser assisted PDT
Konventional PDT for BCC	Active Comparator	Difficult to treat nodular basal cell carcinomas in the face is treated with methyl-aminolevulinate PDT.	Drug: Conventional photodynamic therapy

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Conventional photodynamic therapy	Drug	Photodynamic therapy using methyl-aminolevulinate and red light (37 J/cm2)	AK split-face treatment Konventional PDT for BCC

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Treatment response	Clinical evaluation by a blinded physician.	3 months
Reoccurrence	Clinical evaluation by a blinded physician	12 months
Treatment response	Blinded histological examination from patients with basal cell carcinomas	12 months

Contacts/Locations Module

Condition Browse Module