A Study to Assess the Safety of Using Fibroblast Growth Factor-2 With Periodontal Surgery in Japan (Phase 3)

A Study to Assess the Safety of Using Fibroblast Growth Factor-2 With Periodontal Surgery in Japan (Phase 3)

This study aims to investigate the safety in using Trafermin (recombinant human basic fibroblast growth factor) with periodontal surgery.

Inclusion Criteria:

• Vertical intrabony defect from radiographs at baseline
• Age of 20 years or older

Exclusion Criteria:

• Using an investigational drug within the past 24 months
• Coexisting malignant tumour or history of the same
• Coexisting diabetes (HbA1C 6.5% or more)
• Taking bisphosphonates
• Coexisting gingival overgrowth or history of the same