Metagenomic Analysis of Gut Microbiome in Korean Patients With Ulcerative Colitis

Metagenomic Analysis of Gut Microbiome in Korean Patients With Ulcerative Colitis

The researchers will investigate gut microbiome in Korean patients with ulcerative colitis and normal control subjects using metagenomic analysis to elucidate the significant difference between two groups This study will help to understand the association between gut microbiome and inflammatory bowel disease.

Inclusion Criteria:

• Between the age of 19 and 75 years
• willing to consent/undergo necessary procedures
• clinically active or inactive Ulcerative colitis

Exclusion Criteria:

• Inability to provide informed consent or
• Clinically severe or fulminant ulcerative colitis
• Previous abdominal surgery
• Pregnancy
• Clinically or laboratory-confirmed gastroenteritis for at least 3 months before sampling
• the use of antibiotics in the past a month before sampling
• the use of probiotics in the past a month before sampling
• Severe cardiovascular or pulmonary disease
• Severe convulsive disorder and current use of anti-convulsive medication
• Malignancy
• Transplantation