Exercise Training in Chagas Cardiomyopathy

A Randomized Trial of the Effects of Exercise Training in Chagas Cardiomyopathy

The benefits of exercise training in heart failure are well established. Its effects, however, have not been evaluated in Chagas cardiomyopathy (ChC). The investigators hypothesis is that the exercise training may improve functional capacity, quality of life (QoL), and reduce brain natriuretic peptide (BNP) levels in patients with ChC.

Inclusion Criteria:

• Chronic Chagas dilated cardiomyopathy, defined by the echocardiography finding of a dilated left ventricle with moderate or severe impaired left ventricular systolic function (left ventricular ejection fraction ≤ 45%).
• To be clinically stable for at least 3 months
• To have sinus rhythm
• To be under standard medical therapy use at the time.

Exclusion Criteria:

• Inability to attend regular exercise training
• The presence of a pacemaker, associated cardiac or systemic diseases
• Practitioners of regular physical activity