Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins

Part I:

Proof of concept trial to achieve normal venous pressure values under different provocation maneuvers in healthy persons

Part II:

Non invasive measurement of venous pressure under different provocation maneuvers in patients with chronic venous disease

Inclusion criteria:

Part I:

• Healthy persons without clinical signs of venous disease, informed consent

Part II:

• Patients with chronic venous disease with complete incompetence of the great saphenous vein (Hach IV)
• Informed consent

Exclusion criteria:

Part I:

• Clinical signs of venous disease, former deep vein thrombosis (DVT)

Part II:

• Former deep vein thrombosis, former vein surgery