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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00737-40 | Other Identifier | ANSM |
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The main objective of this study is to obtain data to determine, in each individual with and without wearing compression stockings of different strengths and during different postures, the relationship between interface pressure and the area and circumference of the great saphenous vein and posterior tibial veins in the calf and ankle.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| C1S patients | Experimental | 18 Patients with venous insufficiency: "C1S" patients according to the CEAP (Clinical-Etiology-Anatomy-Pathophysiology)classification. |
|
| C3 patients | Experimental | 18 Patients with venous insufficiency: "C3" patients according to the CEAP (Clinical-Etiology-Anatomy-Pathophysiology)classification. |
|
| C5 patients | Experimental | 18 Patients with venous insufficiency: "C5" patients according to the CEAP (Clinical-Etiology-Anatomy-Pathophysiology)classification. |
|
| Sedentary volunteers | Experimental | 18 healthy volunteers with a sedentary lifestyle (< 2h of physical activity per week) |
|
| Active volunteers | Experimental | 18 healthy volunteers with an active lifestyle (between 2 and 6 hours of physical activity per week) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intravenous pressure and intramuscular pressure measurement | Other | Ultrasound using the Logiq-e system (GE Ultrasound, Chicago, Ill), with a 12L-RS linear probe equipped with a XFTC300 sensor connected to an ARD154 amplifier |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between D and A/F at the calf | D = the diameters of the largest cross section of the posterior tibial veins at calf level; A = the area of the largest cross section of the posterior tibial veins at the calf level; F = interface pressure measured along the leg using a 13 captor system. | Baseline (Day 0) |
| Measure | Description | Time Frame |
|---|---|---|
| Interface pressure for the leg | Interface pressure (mmHg) measured using 13 captors over the entire leg in the following positions: decubitus dorsal, sitting, orthostatic and orthodynamic. | baseline; day 0 |
| Calf interstitial pressure |
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Inclusion Criteria:
Inclusion criteria for patients in the venous insufficiency group:
Inclusion criteria for healthy volunteers
Exclusion Criteria:
Exclusion criteria for healthy volunteers:
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| Name | Affiliation | Role |
|---|---|---|
| Antonia Perez Martin, MD PhD | Centre Hospitalier Universitaire de NÄ«mes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Montpellier - HĂ´pital Saint-Eloi | Montpellier | 34295 | France | |||
| CHU de Nîmes - Hôpital Universitaire Carémeau |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33227457 | Result | Mestre S, Triboulet J, Demattei C, Veye F, Nou M, Perez-Martin A, Dauzat M, Quere I. Noninvasive measurement of venous wall deformation induced by changes in transmural pressure shows altered viscoelasticity in patients with chronic venous disease. J Vasc Surg Venous Lymphat Disord. 2021 Jul;9(4):987-997.e2. doi: 10.1016/j.jvsv.2020.11.010. Epub 2020 Nov 21. | |
| 33964512 |
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| ID | Term |
|---|---|
| D014689 | Venous Insufficiency |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| Athletic volunteers | Experimental | 18 healthy volunteers with an athletic lifestyle (over 6 hours of physical activity per week for at least one year) |
|
Intramuscular interstitial pressure is measured in the calf for 1/3 or randomly selected participants in the following positions: decubitus dorsal, sitting, orthostatic and orthodynamic.
| base line; day 0 |
| Venous pressure at the ankle (mmHg) | Pressure of the great saphenous vein is measured at the ankle in the following positions: decubitus dorsal, sitting, orthostatic and orthodynamic | baseline; day 0 |
| Saphenous vein area, calf | Area (mm^2)of the largest cross section of the great saphenous vein at calf level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Saphenous vein area, ankle | Area (mm^2)of the largest cross section of the great saphenous vein at ankle level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Posterior tibial vein area, calf | Area (mm^2)of the largest cross section of the posterior tibial veins at calf level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Posterior tibial vein area, ankle | Area (mm^2)of the largest cross section of the posterior tibial veins at ankle level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Saphenous vein perimeter, calf | Perimeter (mm)of the largest cross section of the great saphenous vein at calf level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Saphenous vein perimeter, ankle | Perimeter (mm)of the largest cross section of the great saphenous vein at ankle level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Posterior tibial vein perimeter, calf | Perimeter (mm)of the largest cross section of the posterior tibial veins at calf level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Posterior tibial vein perimeter, ankle | Perimeter (mm)of the largest cross section of the posterior tibial veins at ankle level and for the following positions: decubitus dorsal, sitting, orthostatic | baseline, day 0 |
| Heart height difference (mm); saphenous vein, calf | The difference in height (mm) between the right atrium and the target cross section on the saphenous vein in the following positions: decubitus dorsal, sitting, orthostatic. | baseline, day 0 |
| Heart height difference (mm); saphenous vein, ankle | The difference in height (mm) between the right atrium and the target cross section on the saphenous vein in the following positions: decubitus dorsal, sitting, orthostatic. | baseline, day 0 |
| Heart height difference (mm); posterior tibial veins, calf | The difference in height (mm) between the right atrium and the target cross section on the posterior tibial veins in the following positions: decubitus dorsal, sitting, orthostatic. | baseline, day 0 |
| Heart height difference (mm); posterior tibial vein, ankle | The difference in height (mm) between the right atrium and the target cross section on the posterior tibial veins in the following positions: decubitus dorsal, sitting, orthostatic. | baseline, day 0 |
| Leg circumference (mm) | The circumference of the leg is measured every 5 cm in a decubitus dorsal position. | baseline; Day 0 |
| Nîmes |
| 30029 |
| France |
| Mestre S, Triboulet J, Demattei C, Veye F, Nou M, Perez-Martin A, Dauzat M, Quere I. Acute effects of graduated and progressive compression stockings on leg vein cross-sectional area and viscoelasticity in patients with chronic venous disease. J Vasc Surg Venous Lymphat Disord. 2022 Jan;10(1):186-195.e25. doi: 10.1016/j.jvsv.2021.03.021. Epub 2021 May 6. |