Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

Intravenous Saline on Exercise Tolerance in Orthostatic Intolerance

The investigators will test whether an intravenous infusion of saline (salt water) will improve the exercise capacity in patients with postural tachycardia syndrome (POTS).

Inclusion Criteria:

• Meet diagnostic criteria of Postural Tachycardia Syndrome (POTS) 28
• Age between 18-65 years
• Male and female are eligible (although the majority of POTS patients are female).
• Able and willing to provide informed consent

Exclusion Criteria:

• Presence of medical conditions that can explain postural tachycardia (e.g., acute dehydration, medications)
• Pregnancy
• Other factors which in the investigator's opinion would prevent the subject from completing the protocol.
• Patients who are bedridden or chair-ridden