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The objective of this study is to evaluate ocular and nasal signs and symptoms in patients with seasonal allergic rhinoconjunctivitis following allergen exposure in the Allergen BioCube.
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| Measure | Description | Time Frame |
|---|---|---|
| Ocular Itching | At specified timepoints for up to 3 hours | |
| Conjunctival Redness | At specified timepoints for up to 3 hours | |
| Total Ocular Symptom Score (TOSS)of ocular itching and redness | ||
| Total Nasal Symptom Score (TNSS) of nasal symptoms |
| Measure | Description | Time Frame |
|---|---|---|
| Ciliary and episcleral redness | At specified timepoints for up to 3 hours | |
| Chemosis | At specified timepoints for up to 3 hours | |
| Lid Swelling |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects will be 18 years of age or older with a positive history of ocular and nasal allergy and a positive skin test reaction to one of the allergens tested within the past 24 months
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| Name | Affiliation | Role |
|---|---|---|
| Paul Gomes, MS | ORA, Inc. | Study Director |
| Henry J. Crampton, MD | ORA, Inc. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ophthalmic Research Associates, Inc | Andover | Massachusetts | 01810 | United States |
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| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D003233 | Conjunctivitis, Allergic |
| ID | Term |
|---|---|
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
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| At specified timepoints for up to 3 hours |
| Tearing | At specified timepoints for up to 3 hours |
| Nasal Itching | At specified timepoints for up to 3 hours |
| Sneezing | At specified timepoints for up to 3 hours |
| Rhinorrhea | At specified timepoints for up to 3 hours |
| Nasal Congestion | At specified timepoints for up to 3 hours |
| D010038 |
| Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D003231 | Conjunctivitis |
| D003229 | Conjunctival Diseases |
| D005128 | Eye Diseases |